Just when I think I’ve hit the bottom of the rabbit hole, I find that there is a whole other cavern to explore. I was recently put in touch with another woman, Traci, who has had a very similar experience to me: a chemical pregnancy, live birth, and she has gone on to have 7 other miscarriages, all chemical pregnancies except one, which she lost around 10 weeks due to trisomy 11 (a genetic disorder.) I have also met another woman, Melissa, who has the EXACT same history that I do (our children are even a week apart in age.) I have asked them both to share their stories as well and will post a separate page for each of them.
Its a relief to know that while whatever is going on with me is rare, there are a few other women with the same issues and on the same path to trying to find answers. Most doctors don’t seem quite know how to help us, but we have been comparing notes and filling in holes for each other.
Traci pointed me in the direction of endo issues. I strongly suspect that at least one of my losses was due to my lining being too thin from the IUD (3rd cycle after IUD removal and after 2 miscarriages it measured 3mm on cycle day 21. A healthy lining is typically 10-15mm) and as my lining has been checked in the months after, it remains on the thin side (typically 8mm.) There is a test called the Beta-3 integrin protein test.
From their website, Etegritytest.com, “The E-tegrity Test is used to determine how receptive the lining of the uterus is to the implantation of the fertilized egg. The test checks for the presence of the Beta-3 integrin, a glue-like protein necessary for implantation to take place. If you are missing the Beta-3 integrin, the fertilized egg may not attach properly to the uterine wall. As a result, your chances of a successful pregnancy are decreased.”
Hmmmmm, sounds interesting, no?? Of course its more expensive lab testing and we’ve already flushed nearly $2000 down the toilet for these other tests which ultimately didn’t provide any answers (though thanks to my dad, my insurance company IS reimbursing us for at least part of almost all the tests….yes, my dad is awesome.) But whats another $500, right??
The other possible issue that could be going on is undiagnosed endometriosis. Apparently you can have endometriosis even if you don’t have a lot of the traditional symptoms, and this can cause implantation failure.
Here are some of the possible symptoms of endometriosis:
Here are a few links that I found interesting as far as undiagnosed endo in relation to recurrent early miscarriage:
As I read through the symptoms of endo the only thing that really jumps out at me is that I do have VERY painful ovulation pains for almost a week leading up to and through ovulation. Unfortunately that is the only thing that seems like a match. The way to diagnose this is a surgery called laparoscopy in which they make a small incision in your abdomen and insert a camera and look for endometrial tissue. However, they don’t always even find it by doing that and if I do have this then its a very minor case of it. The treatment is taking lupron.
I have a call into my RE to ask about getting the Beta-3 test run and see what he thinks about the endo theory. I’ll keep you all posted.