Found some interesting info about “borderline” APA results as they relate to 1st tri/early m/c. While the study says that it is “not statistically significant” it also reports that people with borderline APA and positive APA results had a higher rate of 1st tri m/c than people who were APA negative. See below.
“Patients with borderline or positive APA were more likely to experience a first-trimester abortion compared to seronegative patients (45, 36.6 and 27% of the pregnancies respectively); however, this difference was not statistically significant. In the seronegative group, four patients had two miscarriages each and one patient had three consecutive second-trimester miscarriages. In the seropositive group four patients had two miscarriages each.”
“The association between recurrent miscarriage and APA is a consistently reported feature of primary antiphospholipidsyndrome (Asherson et al., 1989; Rai et al., 1995). APA, especially IgG anticardiolipin and LAC, are found in 15% of women with recurrent miscarriage. Our study demonstrated that the rate of first trimester miscarriage was higher in patients having positive and/or borderline APA (45 and 36.6% respectively), compared with APA-negative patients(27%). This difference was not statistically significant.”
Statistics were never my strong suit, but I find it confusing that it says that the study demonstrated and people with borderline APA results had a higher rate of 1st tri m/c, but it wasn’t statistically significant. To me, 27% vs 36.6% does seem like a telling difference. Its one thing to look at it mathematically, its another thing altogether to be the person in the 36.6% category. Especially since I had THREE borderline results.